It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Sensorineural hearing loss and plaquenil Chloroquine drug info Chloroquine phosphate testing kit Uses for Hydroxychloroquine Sulfate Malaria. Rheumatoid Arthritis. Lupus Erythematosus. Q Fever. Porphyria Cutanea Tarda and Polymorphous Light Eruptions. Background Q fever endocarditis, caused by Coxiella burnetii, is fatal in 25% to 60% of patients. Currently, treatment with a long-term tetracycline and quinolone regimen for at least 4 years is recommended, although relapses are frequent. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Fever with hydroxychloroquine Hydroxychloroquine Plaquenil Side Effects & Dosage for., Treatment of Q Fever Endocarditis Comparison of 2 Regimens. What if plaquenil doesn t workPlaquenil forlimited sclera dermaCan plaquenil cause glaucomaHydroxychloroquine increase metroxtrate The clinical symptoms are nonspecific and generally include cervical adenopathy and fever with a combination of other associated symptoms consisting of chills, sweats, malaise, nausea, vomiting, diarrhea, weight loss, fatigue, arthralgias, myalgias, hepatomegaly, and/or splenomegaly 2. Kikuchi-Fujimoto Disease Hydroxychloroquine as a Treatment.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine treats malaria, systemic lupus erythematosus, rheumatic disorders like rheumatoid arthritis, porphyria cutanea tarda, and Q fever. In 2014, its efficacy to treat Sjögren syndrome was questioned in a double-blind study involving 120 patients over a 48-week period. Laboratory parameters returned to normal level in 10 days. Patch tests were performed 4 weeks after the symptoms disappeared. They were realized with 10% hydroxychloroquine, 10% chloroquine, and 10% prednisolone in dimethyl sulfoxide DMSO. Patch test for hydroxychloroquine was positive at 48 and 72 h. Current recommendations for treatment of chronic Q fever are 100 mg doxycycline twice per day combined with hydroxychloroquine three times per day at 200 mg per dose for at least 18 months 23, 33. Two daily 100 mg doses of doxycycline have been shown to result in serum concentrations of 2-5 mg/L 34, 35.