Please review the following URL and make sure that it is spelled correctly. Anita- It is hard to say whether I noticed a difference when I first went on plaquenil, because I was also on 10mg of prednisone at that time, and I didn't start weaning down from that until I had been on plaquenil for a few months. Hydroxychloroquine plaquenil sickle cell Plaquenil short term side effects What is Withdrawal syndrome? Withdrawal syndrome a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance has been reported by people with depression, pain, stress and anxiety, fibromyalgia, back pain. Check the latest reports from 24,199 Withdrawal syndrome patients, or browse all conditions. Withdrawal syndrome in Plaquenil - how severe and when it was recovered? Summary We study how severe was Withdrawal syndrome, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources. Discontinuation of hydroxychloroquine could decrease hydrocodone plasma concentrations, decrease opioid efficacy, and potentially lead to a withdrawal syndrome in those with physical dependence to hydrocodone. To answer some of your other questions, it was the same timeframe for me. I can say that the prednisone wean was successful, even after having only been on plaquenil a few months. Plaquenil discontinuation syndrome What is the correct way to discontinue use of plaquenil?, Withdrawal syndrome in Plaquenil how severe and when it. Side affects of plaquenil Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil hydroxychloroquine sulfate dose, indications.. The Risk of Retinal Toxicity with Plaquenil. May 15, 2015 It would be unlikely IMO that the Plaquenil is the cause, since there is tapering necessary when stopping it and no documented 'withdrawal' syndrome associated with it. If you have taken it for a long time, it is probably not even out of your system yet, since Plaquenil has a half-life of 30-60 DAYS not hours. Find information about common, infrequent and rare side effects of Plaquenil Oral. Jul 12, 2015 Polymyalgia Rheumatica Plaquenil hydroxychloroquine Withdrawal Pain Jul 12, 2015. I saw my Rheumy last week and he is concerned about my being up to 9mg of pred for the past 5 months from 4mg.