Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil 200 mg obat apa Taking plaquenil for lupus Chloroquine definition a synthetic drug, CHClN, used in treating malaria, certain kinds of arthritis, etc. Origin of chloroquinefrom chloro- + quinoline. Chloroquine-resistant P. falciparum first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted. Chloroquine binds to heme or FP to form what is known as the FP-Chloroquine complex, this complex is highly toxic to the cell and disrupts membrane function. Action of the toxic FP-Chloroquine and FP results in cell lysis and ultimately parasite cell autodigestion. In essence, the parasite cell drowns in its own metabolic products. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Chloroquine define Chloroquine - definition of chloroquine by The Free Dictionary, CDC - Malaria - Malaria Worldwide - How Can Malaria Cases and. Hydroxychloroquine sjogren's syndrome Chloroquine definition, a synthetic substance, C18H26ClN3, used chiefly to control malaria attacks. See more. Chloroquine Definition of Chloroquine at. Define chloroquine Dictionary and Thesaurus. Chloroquine Article about Chloroquine by The Free Dictionary. Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your. Apr 02, 2019 Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents. Excretion of chloroquine is quite slow, but is increased by acidification of the urine. Definition of chloroquine in the dictionary. Meaning of chloroquine. What does chloroquine mean? Information and translations of chloroquine in the most comprehensive dictionary definitions resource on the web.