These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Return of chloroquine antimalarial efficacy in malawi Plaquenil main side effects Plaquenil corneal toxicity Will hydroxychloroquine help osteoarthritis For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Side effects of long term use of plaquenil Rx Side Effects New Plaquenil Guidelines and More., Plaquenil Uses, Dosage & Side Effects - Hydroxychloroquine side effects ocularHow to taper hydroxychloroquine Brief Answer it is recommended to discontinue Plaquenil Detailed Answer Hello, Thank you for the query at HealthcareMagic Ocular/eye damage is a side effect of Plaquenil seen especially with long term use of medication. Once damage to the eyes are noted, recommendation is to discontinue the. What are the side effects of Plaquenil?. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil hydroxychloroquine is commonly used for lupus in children because of less side effects compared to other medications. Plaquenil hydroxychloroquine helps minimize joint damage. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Retinal Damage. Neurological Disorders. Blood Disorders. Hearing Disorders. Other Side Effects.