I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. Hydroxychloroquine normal dose range Hydroxychloroquine plaquenil and pregnancy Can i take ed pills with plaquenil What is hydroxychloroquine for If you aren’t responding to methotrexate after a two-month period, your rheumatologist may try some kind of combination therapy, such as adding sulfasalazine and hydroxychloroquine called triple therapy or adding a biologic drug such as etanercept Enbrel, adalimumab Humira, or infliximab Remicade. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination therapy with other DMARDs for moderate to severe disease. User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. I had side effects from MTX, which largely wore off, but haven't had any problems with the Hydroxy or Sulpha. I refuse to take it now even if its my passport to biologic treatment. I started with MTX which worked, but not enough so the others were added in which has been better. What does hydroxychloroquine combined with methotrexate do for ra Early RA treatment - Hydroxychloroquine? Hi all, just. - NRAS, Taking Plaquenil for Rheumatoid Arthritis What is plaquenil side effectsPlaquenil price was good rcPlaquenil imprint 1 gg 260Chloroquine nurses responsibility Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in antigen presentation or effects on the innate immune system. Rheumatoid Arthritis Treatment Options Johns Hopkins Arthritis Center. Plaquenil User Reviews for Rheumatoid Arthritis at. Combined basic therapy of rheumatoid arthritis with methotrexate and.. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. MTX+Plaq can be a very effective method of treatment for RA, I guess because the MTX inhibits T-Cell activation and Plaq prevents messengers from telling T-cells to produce TNF - a combination which one imagines is going to be pretty effective - just make sure you have regular blood work with 25mg/w of MTX, it's on the high side, so I hope the side effects aren't too bad for you. Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in.