Plaquenil dosing ideal body weight

Discussion in 'Canadian Pharcharmy Online' started by massjo, 04-Mar-2020.

  1. webarray XenForo Moderator

    Plaquenil dosing ideal body weight

    If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female.

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    The typical dose for hydroxychloroquine is 200-400mg per day and is based on a person’s body weight or if you are overweight, your ideal body weight. While hydroxychloroquine is considered a relatively safe medication, like all medications there are potential risks. These include body rashes that often will itch. The Hydroxychloroquine Dosing Calculator calculates appropriate daily dose of hydroxychloroquine. Ideal Body Weight and Adjusted Body Weight; The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily; 5’ 1/2” to 5.

    For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day.

    Plaquenil dosing ideal body weight

    Plaquenil Risk Calculators, Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc

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  5. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. The biggest difference between the 2011 and current recommendations is the need for patients to be dosed by their real weight instead of their ideal weight.

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    This is represented by the yellow line in the above graph. Since the ideal weight is independent of her true weight the yellow line is perfectly horizontal. By this standard, a 5’4" woman’s ideal plaquenil dose is always 356 mg/day or less. Comparing the yellow line ideal weight to the other two lines. Regarding hydroxychloroquine levels and lupus activity, Costedoat- Chalumeau et al 24 measured whole blood levels in 143 individuals taking a standard dose of 400 mg per day and found a lower hydroxychloroquine level in those with active disease and that lower baseline levels were predictive of disease flare. Typical dose of antimalarial drugs may be too high since these drugs don’t accumulate in fat and bone1,13,14,19 Dosing for overweight and/or short individuals should be based on the basis of height, by finding an estimation of "ideal body weight" and not actual weight1,19 How to define if someone is overweight?

  6. Sm!Le New Member

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses What is the correct way to discontinue use of plaquenil? Healthboards - Immune & Autoimmune - Lupus Plaquenil and.
  7. 4kict Well-Known Member

    Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. Side effects can be severe and potentially fatal so a full assessment of the risks versus benefits is required before methotrexate is prescribed. Efficacy of combination therapy of methotrexate with. A Guide To Perioperative Management Of The Rheumatoid Patient. Treatment of rheumatoid arthritis with methotrexate and.
  8. Snikers07 User

    Study Raises Questions about Sjogren's and Plaquenil Jun 11, 2013 For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system.

    Plaquenil Hydroxychloroquine - Side Effects, Dosage.