Hydroxychloroquine plaquenil mechanism of action

Discussion in 'Canadian Pharmacies Online' started by romb1k, 14-Mar-2020.

  1. akyn XenForo Moderator

    Hydroxychloroquine plaquenil mechanism of action


    Category: Antiprotozoal— antirheumatic (disease-modifying)— lupus erythematosus suppressant— antihypercalcemic— polymorphous light eruption suppressant— porphyria cutanea tarda suppressant— Indications Note: Bracketed information in the Indications section refers to uses that are not included in U. Also has been found to be taken up into the acidic food vacuoles of the parasite in the erythrocyte. falciparum and the other 3 malarial species; however, chloroquine-resistant P. Unaccepted Hydroxychloroquine does not prevent relapses in patients with P. ovale malaria since it is not effective against exo-erythrocytic forms of the parasite.

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    Mechanism of action/Effect Antiprotozoal—Malaria Unknown, but may be based on ability of hydroxychloroquine to bind to and alter the properties of DNA. Also has been found to be taken up into the acidic food vacuoles of the parasite in the erythrocyte. Hydroxychloroquine is a 4-aminoquinoline with immunosuppressive, antiautophagy, and antimalarial activities. Although the precise mechanism of action is unknown, hydroxychloroquine may suppress immune function by interfering with the processing and presentation of antigens and the production of cytokines. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.

    [ It may be used in addition to nonsteroidal anti-inflammatory agents.] Lupus erythematosus, discoid (treatment) or Lupus erythematosus, systemic (treatment)—Hydroxychloroquine is indicated as a suppressant for chronic discoid and systemic lupus erythematosus . falciparum , originally seen only in Southeast Asia and South America, are now documented in all malarious areas except Central America west of the Canal Zone, the Middle East, and the Caribbean. Chloroquine is still the drug of choice for the treatment of susceptible strains of P.

    Hydroxychloroquine plaquenil mechanism of action

    Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Hydroxychloroquine C18H26ClN3O - PubChem

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  6. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.

    • Hydroxychloroquine Plaquenil.
    • Hydroxychloroquine - Wikipedia.
    • Hydroxychloroquine Plaquenil -.

    Hydroxychloroquine A 4-aminoquinoline with antimalarial and immunosuppressive properties. Although its precise mechanism of action is unknown, hydroxychloroquine may suppress immune function by interfering with the processing and presentation of antigens and the production of cytokines. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Hydroxychloroquine, an alkylated 4-aminoquinoline, is a hydroxylated form of chloroquine and has a biological mechanism of action similar to chloroquine’s. Hydroxychloroquine was originally developed as a safer alternative to chloroquine for the treatment of malaria and was later found to have antirheumatic and anti-inflammatory uses.

     
  7. coyot User

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. CategoryRetina/Vitreous - EyeWiki Hydroxychloroquine toxicity - EyeWiki Hydroxychloroquine - Wikipedia
     
  8. Dbest.ru Moderator

    La hidroxicloroquina (Plaquenil) se considera una droga antirreumática modificadora de la enfermedad (DMARD, por sus siglas en inglés) porque puede disminuir el dolor y la inflamación de la artritis; puede prevenir el daño articular y reducir el riesgo de sufrir una incapacidad a largo plazo. Hidroxicloroquina Plaquenil Hydroxychloroquine Oral Route Proper Use - Mayo Clinic Hydroxychloroquine Uses, Dosage & Side Effects -
     
  9. Creditcardoffer Moderator

    Chloroquine and Hydroxychloroquine Toxicity Practice. Pasadhika S, Fishman GA. Effects of chronic exposure to hydroxychloroquine or chloroquine on inner retinal structures. Eye Lond. 2010 Feb. 24 2340-6. Michaelides M, Stover NB, Francis PJ, Weleber RG. Retinal toxicity associated with hydroxychloroquine and chloroquine risk factors, screening, and progression despite cessation of therapy.

    Hydroxychloroquine toxicity - EyeWiki