Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Why use plaquenil for scleroderma Plaquenil retinal screening guidelines after stopping One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Re Plaquenil - Can It Work Quickly? Maybe you should discuss this with your doctor. Sounds like he took away a med that was doing a good job,unless there is something else that is preventing you from taking it of course. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Will plaquenil take joint swelling away LUPUS MEDICINES, Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly? Plaquenil ocular screening Husband began keytruda every 3 weeks in Jan 2016, received infusions evwry 3 weeks with no side effects other than some fatigue. Was off keytruda for 3 months due to brain tumor which was successfully removed 100 percent. Now has been back in keytruda for 6 months and has experienced very severe swelling and joint pain. The doctor says it is a side effect. He is on oxycodone, morphine and a. Keytrua Infusuon causing joint pain and swelling.. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Plaquenil Drug and Medication User Reviews on RxList. I noticed plaquenil helping with my fatigue more so than anything else. It does help my joint pain but I need extra help from other meds too It can take up to 6 months to get in your system and fully work, each person is different. I pray it doesn't take that long for you to get some relief. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Less than one person in 5,000 develops the problem. One approach to controlling lupus arthritis is with slow-acting agents such as hydroxychloroquine Plaquenil®. This medication can help with joint pain and swelling and may also help with the fatigue of lupus. There is evidence that this drug slightly lowers cholesterol as well.