Facts on chloroquine

Discussion in 'Canadian Pharmacies-24h' started by a1bT, 01-Mar-2020.

  1. sp52_dt New Member

    Facts on chloroquine


    Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

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    Oct 01, 2018 Each tablet contains 500 mg of Chloroquine phosphate USP, equivalent to 300 mg Chloroquine base. Inactive Ingredients colloidal silicon dioxide, dibasic calcium phosphate, hydroxypropylmethylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate80, pregelatinized starch. Chloroquine is metabolized in the liver, primarily by CYP2C8 and CYP3A4 enzymes, and it can selectively inhibit CYP2D6 activity. Drugs that inhibit CYP3A4 such as ritonavir may increase plasma levels of chloroquine. Potential interactions may also exist between chloroquine and drugs that are substrates for CYP2D6. 11,16,17 Chloroquine causes a toxic myopathy but also produces a toxic neuropathy. Chloroquine is an antimalarial drug also used for the treatment of severe rheumatoid arthritis, systemic lupus erythematosus, and other dermatological diseases. The clinical features of chloroquine-induced neuropathy are those of symmetrical sensorimotor polyneuropathy.

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Facts on chloroquine

    Chloroquine MedlinePlus Drug Information, Chloroquine Information for Providers AIDSinfo

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  6. Mar 06, 2020 Scientists Say Chloroquine Might Aid Treatment of Coronavirus Infection Since the ongoing coronavirus outbreak started in December 2019, researchers have been While scientists battle to find a cure for the novel coronavirus CoVID-19, it has emerged that the old malaria drug chloroquine might help in some way.

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    Apr 02, 2019 Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents. Excretion of chloroquine is quite slow, but is increased by acidification of the urine. In vitro data suggest that chloroquine inhibits SARS Cov-2 replication. In past research, chloroquine has shown in vitro activity against many different viruses, but no benefit in animal models. Chloroquine has been proposed several times for the treatment of acute viral diseases in humans without success. Some Chinese doctors are also trying chloroquine, an antimalarial drug, which is off-patent, therefore cheap and highly available, and would be very useful in low-income countries.

     
  7. GuDus Guest

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Conditions that Hydroxychloroquine Oral Treats Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Chloroquine And Hydroxychloroquine Toxicity - StatPearls.
     
  8. karalkan Well-Known Member

    Compare Plaquenil vs Chloroquine - Plaquenil hydroxychloroquine helps minimize joint damage. It can also decrease symptoms and future complications. Plaquenil hydroxychloroquine is a good choice for people who have difficulty tolerating newer biologic medications. A generic form of Plaquenil hydroxychloroquine is available.

    Healthboards - Immune & Autoimmune - Lupus generic plaquenil?
     
  9. Saturn User

    Chloroquine Phosphate – Marine Fish Diseases and Treatment The tablets are fine to use, but the downside is you get less “chloroquine base” out of them so you must dose more. The following was taken from Bob Goemans online book, THE LIVING AQUARIUM MANUAL In most cases, 250 mg tablets have an equivalence of 150 mg chloroquine base, and 500 mg tablets have an equivalence of 300 mg chloroquine base.

    Chloroquine – A-Z Medicine