I have been on plaquenil for over a year and a half and methotrexate since September. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes (used to be every 2 weeks). I have lupus which mainly affects my joints and skin. One affects your eyes more and one affects your liver more. I would appreciate any comments or advice from everyone. Wannabe Hi, I am on both methotrexate and plaquenil. Wannabe To Be Free To Roam Sorry to hear that you are having a lot of pain with your RA. Can a blood test show if im taking plaquenil Vitamin c and plaquenil Neuropathy caused by plaquenil Hydroxychloroquine monitoring Original Article from The New England Journal of Medicine — Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications I'm on methotrexate too now but was on a different immunosuppressant for 18mths before that. Being immune suppressed freaked me out at the start n I thought I'd pick up infection really quickly. I haven't. hubby's had a couple of colds n I've been ok. Im on plaquenil, cellcept AND tacrolimus--finally helping my lupus nephritis and as. Methotrexate is a type of disease-modifying anti-rheumatic drug DMARD. It’s used to reduce activity of the immune system for people who have certain conditions. The immune system normally protects the body from infections or bacteria by causing inflammation to fight them. I wish you well with this decision and the results. Your chances of problems with the methotrexate are a bit larger. deductible (I am at about $2,500 - $3,000 right now). My rheumy recently added Imuran (instead of methotrexate). So, what do yall know about the side effects of both and the benefits of both? Methotrexate and hydroxychloroquine Methotrexate and Plaquenil drug interactions - eHealthMe, Methotrexate and Coronavirus Apologies if this. - LUPUS UK Ocular toxicity plaquenilBruises on shin from plaquenil I know Plaquenil has helped me a ton, because I tried going off of it once to see if I really needed it. The first two weeks weren't bad, as Plaquenil has a high half-life and there was still some Plaquenil in my body. After that, my Lupus got progressively worse until I gave up and re-started the Plaquenil after 6 weeks of being off it. Methotrexate vs. Plaquenil - Autoimmune diseases - Inspire. Methotrexate Side-effects, uses, time to work. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Curcumin in turmeric may increase the therapeutic action of arthritis medications and protect from their side effects as well. Let’s examine the scientific details behind the safety of taking turmeric and curcumin with arthritis medications. 1. Curcumin may change drug absorption. Turmeric and curcumin are safe for consumption.