I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Plaquenil crest Does plaquenil cause high blood pressure Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. It's ok to stop plaquenil without weaning, but I do recommend that if you feel you can wait til Monday, wait, and talk with your rheumy then. I felt that plaquenil wasn't helping, and was causing digestive problems for me, so with my dr. ok, I went off it. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydroxychloroquine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Do you have to wean off hydroxychloroquine Drug tapering An option, not a necessity, for patients., Can you quit plaquenil cold turkey, or have to wean Plaquenil dosage for osteoarthritisPlaquenil eye exam guidelines So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few. Let me tell you what weaning down from Plaquenil is like.. Hydroxychloroquine MedlinePlus Drug Information. Plaquenil hydroxychloroquine sulfate dosing, indications.. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. However, more often than not they are weaned if they have helped and stopped abruptly if they weren't helping at all or were associated with side effects. For example, methotrexate, doxycycline, and hydroxychloroquine can be stopped suddenly as the preferred method of ending a treatment if it was not helping. What Are The Side Effects Of Stopping Methotrexate. The doctor just tells me not to go off them, but I have no choice. I am also taking folic acid and Hydroxychloroquine. And I am out of all.