Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. How does hydroxychloroquine kill malaria Prasco brand plaquenil Is it ok to take plaquenil before surgery Joint pain after stopping plaquenil Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An. Blood or bone marrow problems or Diabetes or Eye or vision problems or Muscle problems or Nerve problems or Porphyria blood disorder or Psoriasis skin disease or Stomach or bowel problems–Use with caution. May make these conditions worse. Bone marrow biopsies showed fibrosis in 19 cases, including one case of pure red cell aplasia and one case of agranulocytosis and variable global marrow cellularity. Treatments included corticosteroids 90%, hydroxychloroquine 87%, rituximab 33%, intravenous immunoglobulins 30%, mycophenolate mofetil 20% and ciclosporine 20%. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil bone marrow Plaquenil, a warning. lupus - reddit, Hydroxychloroquine Oral Route Before Using - Mayo Clinic Plaquenil safe during pregnancyTrade name of chloroquine What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Bone marrow involvement in systemic lupus erythematosus.. Will you have Myelodysplastic syndrome with Plaquenil.. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Summary Bone marrow depression is found among people who take Plaquenil, especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months, also take medication Prednisone, and have Lupus nephritis. Although the risk of bone marrow depression is low, periodic blood counts are advisable as anaemia, aplastic anaemia, agranulocytosis, a decrease in white blood cells, and thrombocytopenia have been reported. Plaquenil should be discontinued if abnormalities develop.