Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. What people lose their hair when on plaquenil Chloroquine anti-malarial drug An eye pressure test may be used to rule out other eye diseases, such as glaucoma. Signs and symptoms of Fuchs’ dystrophy can be difficult to detect at first. If you are using Plaquenil, The Wellish Vision Institute recommends regular eye exams to help catch any change that may be subtly occurring. Symptoms of retinopathy to be aware of are blind spots in your central vision, distortion of objects, blurring, light flashes and sensitivity, as well as colors becoming distorted and difficulty seeing at night. One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil eye light sensitivity Immune & Autoimmune - Lupus plaquenil light sensitivity, Plaquenil Las Vegas Diabetic Retinopathy Wellish Vision Institute Chloroquine and cancer More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil Side Effects on Your Eyes and Vision. The Risk of Retinal Toxicity with Plaquenil. Eye Floaters, Light Sensitivity & Computer's. Photophobia extreme sensitivity to light has been reported by people with multiple sclerosis, depression, rheumatoid arthritis, pain, high blood pressure. Check the latest reports from 13,516 Photophobia patients, or browse all conditions. Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision.