Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil hyperpigmentation histology Skin changes with plaquenil Chloroquine effect on cell lysis Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects with plaquenil Methotrexate vs Plaquenil Comparison -, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil eye toxicity symptomsChloroquine phosphate tablets 500mgPlaquenil and hyperpigmentationPlaquenil manufacturer discountAra patient information hydroxychloroquine RARE side effects If experienced, these tend to have a Severe expression A Disease With Shrinking And Weaker Muscles Called Myopathy A Disorder Of The Peripheral Nerves That Enable Movement Called. Common and Rare Side Effects for Plaquenil Oral. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Many people using this medication do not have serious side your doctor immediately if any of these unlikely but serious side effects occur arm/leg/back pain, fast heartbeat, hair loss/color change, mental/mood changes e.g. anxiety, depression, hallucinations, ringing in the ears/hearing loss, worsening of skin conditions e.g. psoriasismedication may infrequently cause serious sometimes permanent eye problems or muscle damage, especially if you take it for a long time. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. You will likely have to take additional medications to keep your rheumatoid arthritis in control.