The proposed mechanism is inhibition of CYP450 2D6 hepatic metabolism by hydroxychloroquine. In a randomized, double-blind, crossover study, seven healthy subjects with CYP450 2D6 extensive metabolizer phenotypes took 400 mg hydroxychloroquine or placebo twice daily for 8 days, and 100 mg metoprolol orally on the ninth day. Lariago chloroquine phosphate 250 mg Plaquenil indication apl syndrome Alternative for plaquenil Hydroxychloroquine cyp Drug interactions are reported among people who take Metoprolol tartrate and Plaquenil together. This study is created by eHealthMe based on reports of 288 people who take Metoprolol tartrate and Plaquenil from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs and supplements since 2008. Your medicine may need to be healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. 1. Lopressor metoprolol tartrate US prescribing information. Nov 08, 2014 The difference is that Metoprolol SUCCINATE slow-releases its dose over a 24-hour period, whereas, Metoprolol TARTRATE releases over a 12-hour period. so you can either take your entire daily dose, as succinate, once a day. or. you can take tartrate twice a day with each dose being half of the total daily milligrams you need. No adverse effects were reported and the clinical significance is unknown. Average metoprolol AUC increased by 65% and maximum plasma concentrations increased by 72%. Can plaquenil and metoprolol tartrate be taken together Other Drugs That Can Interact With Metoprolol Tartrate, Interactions between Plaquenil Oral and selected-cyp2d6. Plaquenil weight Some of the drugs that can potentially interact with metoprolol tartrate include clonidine, calcium channel blockers, and nonsteroidal anti-inflammatory drugs NSAIDs. Metoprolol Tartrate Interactions An Overview. Metoprolol tartrate Lopressor ® can potentially interact with a number of other medicines. Drug Interactions With Metoprolol Tartrate. Metoprolol succinate n tartrate? -. Can metoprolol, xarelto and propafenone be taken together?. Metoprolol is a beta blocker and Lisinopril is an ace inhibitor. In fact, they are commonly used together in heart disease patients. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Demarco on can i take metoprolol with losartan These are two different classes of medications used for treatment of high blood pressure and heart disease. Using metoprolol and diltiazem together may lead to increased side effects. This can cause fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, decreased heartbeat/A – V block, or irregular heartbeat. If you take both medications together, tell your doctor if you have any of these symptoms. Not all medicines respond well when taken together, and there is always the possibility of developing negative drug interactions. With metoprolol, these interactions can cause your body to metabolize the medicines differently than intended and result in problems like excessive drug levels in your system, extremely low blood pressure, slow heart rate, or low blood sugar levels, among other things.