But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Does plaquenil cause sun sensitivity Does plaquenil make you tired Methylene blue falciparum chloroquine Chloroquine and alcohol Apr 02, 2010 there are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. Aug 02, 2018 Anti-rheumatic drug A medication first used for malaria, hydroxychloroquine Plaquenil® is used to treat rheumatoid arthritis, some lupus symptoms, childhood arthritis and other autoimmune diseases. NSAID painkillers Nonsteroidal Anti-Inflammatory Drugs are often used for joint pain, muscle aches, headaches and tenderness. NSAIDs can be. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Is there a natural drug substitute for plaquenil Plaquenil substitute - Things You Didn’t Know, Natural Lupus Treatment for Symptoms and Management - Dr. Axe Hydroxychloroquine sulfate tab 200 mgMthfr and plaquenilChloroquine phosphate buy over the counter The alternative to Plaquenil is a slightly different anti malarial called Quinacrine. Plaquenil replaced Quinacrine formerly called Atabrine for anti malarial prophylaxis so now the Quinacrine has to be made up into pills or gel capsules by a compounding pharmacy. If you google you will find details of compounding pharmacies. Discontinued Plaquenil.other options?. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Is there an alternative to Plaquenil? - Sjogren's World. The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. Anybody would be with that diagnosis. But the drugs are safe. The side-effects are minimal. Not taking the drugs and pretending that there is a natural cure is dangerous. You need to understand that the drug was prescribed because it was proven effective in the treatment of lupus. There are side-effects with any drug, even natural ones. Glenn Frey's death, tied in part to rheumatoid arthritis medications he was taking, is a 'wake-up call' about the dangers of powerful drugs used to treat the condition, a top doc says. It should push arthritis patients and their doctors to seek out safer available alternatives.