Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine other names Does plaquenil cause acne Does plaquenil keep you awake Plaquenil and Weight loss - from FDA reports Summary Weight loss is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Plaquenil caused a loss of appitite and weight loss for me. Both times I started taking it, the first time it was so serious I had to stop taking it. Started again several years later when I flared again and had loss of appitite and weight loss but a bit more moderate. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can taking plaquenil cause weight loss Rheumatoid arthritis Weight loss and other side effects, Hydroxychloroquine Side Effects Common, Severe, Long Term. Where can i buy hydroxychloroquine 200 mgPlaquenil skin rash symptoms Re want to know good stuff about plaquenil Sorry to be a party pooper here, but I have been on Plaquenil for 5 months and can't say I feel any difference at all. If anything I am sleeping all day but for just about 1 1/2 hours at a time. Want to know good stuff about plaquenil - HealthBoards. Plaquenil & Weight Gain/Loss -. Hair loss and Plaquenil? DailyStrength. Plaquenil can cause loss of appetite and I agree that losing weight at this rate and suffering diarrhea is not healthy and might mean you become ill nourished and dehydrated. I suggest lowering the dose, going back to the original, until your tum has settled down then very gradually increasing it to give your body the maximum chance to adjust. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation.