Regardless of the problem, we'd like to help you find what you're looking for. Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. Plaquenil pulmonary sarcoidosis Chloroquine pharmacological class Plaquenil and breast cancer I also don't find my mouth is as dry. I spoke to my mouth specialist about this and she found this all very interesting. She said that she previously didn't think that Plaquenil helped with dry mouth and eyes, but lately has been hearing the opposite and that I "provided very convincing evidence" that it does help. Dry mouth is a common symptom that afflicts numerous older adults. Additionally, patients with connective tissue diseases such as lupus and rheumatoid arthritis often suffer from severe dryness of the eyes and mouth. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Your immune system mistakenly attacks your body's own cells and tissues. The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. Plaquenil and dry mouth Sjogren's syndrome - Symptoms and causes - Mayo Clinic, What to do about a "dry mouth"" Lupus Community - Support Group Chloroquine g6pd Cholinergic agonists help to stimulate secretions in the body. For dry eye and dry mouth, doctors may prescribe pilocarpine hydrochloride or cevimeline, both of which stimulate the lacrimal glands to produce more tears and the salivary glands to create more saliva. Both medications are taken by mouth three times a day. Medications for Sjogren’s Syndrome NYU Langone Health. The Risk of Retinal Toxicity with Plaquenil - Sjogren's. Dry mouth in Plaquenil how severe and when it was recovered? - eHealthMe. Yeast infections in the mouth should be treated with antifungal medications. Treat systemwide symptoms. Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Dry mouth, besides being uncomfortable, can damage tooth enamel and gums, leading to cavities and gum disease. It is essential to have regular checkups with a dentist who understands Sjogren’s syndrome, and to practice good oral hygiene. Jun 16, 2016 The thing is I have not been diagnosed with Sjogren's yet. As I understand taking Plaquenil and seeing if it helps are a part of diagnosis. What makes me unwilling to take the risk, however small it may be, is that I only seem to have two symptoms of Sjogren's dry eyes and Raynaud's phenomenon. I've never noticed any mouth dryness myself.