Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Sweating stoping plaquenil Osteo bi-flex triple strength and plaquenil Dermatomyositis hydroxychloroquine rash Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or; hair loss. Itchy skin & plaquenil Hi, I need some help please, I have been on Plaquenil actually hydroxychloroquine sulfate since May and have had great physical benefit with this drug. However for the past two weeks,I have had very uncomfortable itchy skin that radiates to different parts of my body. Itchy palms are certainly annoying. They can drive you mad when the irritating, burning itch doesn’t stop. But an itchy palm is rarely a sign of a bigger, more serious problem. That’s the good news. The bad news is that itchy palms can be a sign of a chronic skin condition that needs frequent treatment. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Itchy palms plaquenil Plaquenil Side Effects Common, Severe, Long Term -, Healthboards - Immune & Autoimmune - Lupus Itchy skin Bulleye chloroquin retinopathyChloroquine bafilomycin a1 conventional autophagyChloroquine volume of distributionDoes hydroxychloroquine help with fatigue Itchy palms are a common symptom that in many cases have no clearly identifiable cause and resolves on its own within minutes to hours. This itching for no reason has been linked to many superstitions in different cultures. However, from medical perspective an itchy palm can be an important indicator that the skin of the hand is either injured. Itchy Palms Inside of Hand Causes and Pictures.. Itchy Palms What’s the Cause?. PLAQUENIL Side Effects, Reviews by Patients -. A full day passed with no symptoms, then the next night, i felt itching in my body, my elbows, my knees, my butts and palms. When i woke up in the morning, i found out that my palms were red, itchy and heavy. They kept on swelling, also my knees swelled a bit. My hand fingers are like balloons. i could not even close the hands. The palms may become reddish in color called palmar erythema, while the skin on the back of the hands can turn pale in color and even appear translucent. Rheumatoid Nodules Rheumatoid arthritis can cause lumps to form beneath the surface of the skin, particularly in the area of affected joints 1. Itchy Palms Possible Causes and Treatments. Itchy palms are a common symptom for a variety of disorders. Oftentimes, those experiencing it can easily manage the symptom by applying creams or other non-pharmacological means. Unfortunately, there are some cases wherein the itch persists for a very long time and is seriously distracting you from.