Plaquenil maculopathy oct images

Discussion in 'Chloroquin' started by Smoke552, 12-Mar-2020.

  1. degreealtelay Moderator

    Plaquenil maculopathy oct images


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

    Hydroxychloroquine and phototherapy combination morphea Chloroquine autophagy Hydroxychloroquine swollen lymph nodes Effects of plaquenil on eyes

    Bull's-eye maculopathy due to hydroxychloroquine toxicity. Contributor Jesse Vislisel, MD Photographer Randy Verdick, FOPS September 9, 2013. This patient took hydroxychloroquine for rheumatoid arthritis and her vision dropped to 20/300 as a result of the retinal toxicity. Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. The new images will be compared to the original ones to check for any changes. You will continue to be screened every year until you stop taking hydroxychloroquine. Possible retinopathy If there is an abnormality found in any one test it means there is a possibility of there being signs of hydroxychloroquine retinopathy. If the

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Plaquenil maculopathy oct images

    Plaquenil Toxicity - Bulls Eye Maculopathy - Retina., Chloroquine retinopathy - Wikipedia

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  7. Toxic maculopathy is a form of retinal toxicity that is associated with antimalarial agents such as plaquenil and chloroquine. Both medications are commonly used to treat patients with systemic autoimmune diseases that include the following

    • H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS.
    • Eye screening for patients taking hydroxychloroquine Plaquenil.
    • OCT of Plaquenil Maculopathy - Retina Image Bank.

    If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Spectral domain optical coherence tomography SD OCT images, red-free photos, and fundus autofluorescence FAF demonstrate a spectrum of findings seen with different stages of hydroxychloroquine retinopathy. Note the increased signal of choroidal vessels. The presence of bull’s-eye maculopathy indicates the disease has been progressing for years, resulting in foveal thinning and likely vision loss. 8 SD-OCT is a highly sensitive and reproducible imaging modality used in the detection of Plaquenil retinal toxicity. The preferential loss of photoreceptor IS/OS junction makes SD-OCT an ideal tool.

     
  8. Raptorv Guest

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Hydroxychloroquine - Wikipedia Plaquenil Oral Uses, Side Effects, Interactions. Will you have Alcohol interaction with Plaquenil - eHealthMe
     
  9. sash_karp XenForo Moderator

    Interaction between DNA damage response and autophagy in. As mentioned before, autophagy plays a dual and contradictory function in tumorigenesis. In normal cells, autophagy acts as a surveillance pathway by clearance aggregated and misfoldedproteins, removing damaged organelles, as well as decreasing DNA lesions, free radicals, and mitochondrial abnormalities in order to cellular protection from malignant transformations Choi et al. 2013.

    Chloroquine and hydroxychloroquine for cancer therapy