So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Choi et al 2014 chloroquine paclitaxel Sickle cell disease guidelines hydroxychloroquine Vision loss typically is permanent, with little significant improvement, and may continue to progress even years after drug cessation. Previous Plaquenil Testing Guidelines In 2002, the American Academy of Ophthalmology AAO established ocular examination guidelines for screening patients on Plaquenil therapy. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. For the four years that I took the drug, my eye sight never bothered me and bi-annual eye tests revealed no changes. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Plaquenil blurry vision years after stopping Medications that can Affect the Eye or Visual System, Plaquenil Withdrawal – Life As An Anomaly Hydroxychloroquine aplastic anemiaPlaquenil and lung cancer No side effects for first 6 1/2 years, then my eyes started hurting very bad. I have been off the generic Plaquenil now for 2 months. My vision is less blurred, both pupils are now the same size and less pain in eyes. BUT, now my whole body hurts so much. Trying to decide which is worse the eye pain or body pain. PLAQUENIL Side Effects, Reviews by Patients page 3.. Rx Side Effects New Plaquenil Guidelines and More.. The Risk of Retinal Toxicity with Plaquenil. My son his on Plaquenil and he complained about Constant pain and worse when bending forward. He compares the pain to that of a small pericarditis. He do all of his day at school including sports but the plain is always there. The pain started about 1 month after he began to take Plaquenil hydroxychloroquine. A drug called Plaquenil commonly used to treat Lupus also can cause optic neuropathy. and sometimes for several years after stopping it. It can cause blurred vision, eye pain, conjunctivitis and double vision. Topiramate Topamax treats seizure disorders, migraines and mood disorders. It can cause acute glaucoma, which can damage the. Plaquenil is the brand name of. Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Retinal damage may not improve even after.