Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Serious side effects of plaquenil Hydroxychloroquine sulphate tablets ip 200 mg Hi there, been on plaquenil for many years. Now I have recently gained some weight so my rheumatologist increased my dosage with the new guidelines. She told me to split the pill in half. I did read somewhere I can’t remember where it said not to split the plaquenil. Has anyone done this with results. Am suppose to take 340 mg now. So cut a pill just before you take it, then take the other half as your next dose. That helps ensure that you compensate for any deviation in size. And split pills in half—not into smaller. Dec 04, 2016 Pills should only be split in half, not into smaller portions, such as thirds or quarters. The easiest pills to split are relatively flat round ones with a scored center, a slightly indented line that runs across the center of the pill. However, not every pill that has a scored center is meant to be split. “ Don’t split your pills in advance. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Why plaquenil should not be cut in half Plaquenil Arthritis Information, When It's Safe to Split Pills - Consumer Reports Does plaquenil suppress immune system further in an immunosuppressed person You should not use Plaquenil if you are allergic to hydroxychloroquine. Plaquenil should not be used for long-term treatment in children. To make sure Plaquenil is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; Plaquenil Uses, Dosage & Side Effects -. Pill splitting which ones are safe to divide? – Heart Sisters. Hydroxychloroquine MedlinePlus Drug Information. Therefore Plaquenil should not be used in pregnancy. Lactation Careful consideration should be given to using hydroxychloroquine during lactation, since it has been shown to be excreted in small amounts in human breast milk, and it is known that infants are extremely sensitive to the toxic effects of 4-aminoquinolines. Unfortunately, cessation of Plaquenil intake may not be a remedy since not infrequently, patients will develop objective evidence of progression despite discontinuation of the drug. Thus, the possibility of toxicity should not be disregarded and close monitoring of the ocular findings is required. Do not use Plaquenil without telling your doctor if you are breast-feeding. Our blog on Lupus and Pregnancy has much more valuable information on this topic. Back to top. We hope that this blog has been helpful in answering some of your questions about Plaquenil and other antimalarial drugs used to treat lupus.