Plaquenil hyponatremia

Discussion in 'Chloroquine' started by KPOTEHOK, 18-Mar-2020.

  1. Sadow Well-Known Member

    Plaquenil hyponatremia


    Common causes include medications and the syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Hyponatremia can be classified according to the volume status of the patient as hypovolemic, hypervolemic, or euvolemic.

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    Aug 14, 2017 Hyponatremia is especially life-threatening in acute cases which develop within 48 hours. Chronic hyponatremia that develops over days or weeks is less likely to cause life-threatening brain swelling. Other Causes. Besides electrolyte balances such as too little sodium, heart palpitations may result from other causes. Hyponatremia or low sodium levels in the blood can result in signs and symptoms like headache, confusion, seizures, weakness, restlessness, and muscle spasms. Kidney or congestive heart failure, hypothyroidism, cirrhosis, medications, or strenuous exercise without electrolyte replacement can cause hyponatremia. Treatment for hyponatremia are diet changes and electrolyte replacement with an IV. Plaquenil ® hydroxychloroquine sulfate is a white or practically white, crystalline powder, freely soluble in water; practically insoluble in alcohol, chloroform, and in ether. The chemical name for hydroxychloroquine sulfate is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. Its structural formula is

    Differentiating between euvolemia and hypovolemia can be clinically difficult, but a useful investigative aid is measurement of plasma osmolality. Hypervolemic hyponatremia may be caused by congestive heart failure, liver cirrhosis, and renal disease.

    Plaquenil hyponatremia

    Hyponatremia - Symptoms and causes - Mayo Clinic, Hyponatremia Definition, Symptoms, Causes & Treatments

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  3. Leukopenia, which frequently occurs in patients with systemic lupus erythematosus, is usually not severe i.e. white blood cell count of less than 1,000 × 10 3 per mm 3 1.0 × 10 9 per L and rarely requires treatment. Thrombocytopenia, if stable, and if the platelet count remains above 50,000 × 10 3 per mm 3.

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    Patible with the inappropriate secretion of antidiuretic hormone SIADH. Additionally, the response of the serum Additionally, he presented with hypo­ natremia. In such cases, the detection of the underlying cause of the hyponatremia is of paramount importance for the evalu­ ation and proper management of the pa­ tient. The diagnosis is based on the pa­ Hemodialysis, a potential treatment used in severe cases, was not used in any of the 4 patients. Two patients died. The condition of patient 1, who had the highest plasma ammonia level at 168 μmol/L, deteriorated further clinically despite therapeutic measures and plasma ammonium levels decreasing to 110 μmol/L. Hyponatremia is a condition where plasma sodium level falls to less than 135 mmol/L. The body maintains a careful balance of electrolytes like sodium, potassium and chloride within the cells as well as in fluid outside the cells like blood and body fluids. Sodium is necessary to carry out some important functions like maintaining blood pressure.

     
  4. Shulga Well-Known Member

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Plaquenil - FDA prescribing information, side effects and uses Platelets plaquenil Anti-Inflammatories discussions. Thrombotic Thrombocytopenic Purpura National Heart, Lung.
     
  5. njin New Member

    Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Quinacrine Atabrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the patient does not respond to Plaquenil alone.

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