Severe malaria should be treated with intravenous (IV) antimalarial medications. As a result, CDC is providing IV artesunate for the treatment of all severe malaria cases. With the discontinuation of IV quinidine, IV artesunate is now the first-line drug for treatment of severe malaria in the United States. Plaquenil imprint 1 gg 260 Plaquenil treatment lyme disease Skin discoloration plaquenil Infusions should be discontinued as soon as the patient is able to take chloroquine by mouth. Where facilities for intravenous infusion are not available chloroquine can be administered by intramuscular or subcutaneous injection at a dosage of 2.5 mg/kg every 4 hours or 3.5 mg/kg every 6 hours until a total of 25 mg/kg has been given. Prophylaxis Cardiovascular effects of chloroquine in the open chest dog preparation and the effects of quinidine and chloroquine on excitability and conductivity in isolated heart muscle. METHODS A. Heart in Situ. Mongrel dogs, weighing 10 to 14 Kg. were anesthetized with an intravenous injection of a combination of equal amounts of Parenteral chloroquine may be administered safely by simply giving smaller, more-frequent doses than are currently used or, in the case of iv administration, by using continuous infusion. PMID 3543146 It is unknown when IV artesunate will receive FDA approval, as this process requires an interested drug company to submit a new drug application to FDA. IV artesunate is the recommended World Health Organization (WHO) first-line treatment for severe malaria but is neither FDA-approved nor commercially available in the United States. Chloroquine injection intravenous Pharmacokinetics of Quinine, Chloroquine and Amodiaquine., Cardiovascular Effects of Chloroquine with Special Reference. Maxalt plaquenil interactionWhat is the shelf life of chloroquine phosphateChloroquine and proguanil in pregnancy Although most symptoms responded to routine treatment of diabetes his temperature remained at 40°C and focal convulsive fits continued. Cerebral malaria was suspected and 250 mg of chloroquine was administered by slow intravenous injection over 5 minutes. Towards the last few drops of the injection the patient's pulse became. Cardiac arrest after intravenous chloroquine injection.. Parenteral chloroquine for treating falciparum malaria.. Chloroquine Phosphate Injection, Packaging Type Box ID.. Find patient medical information for Chloroquine Injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Jul 30, 2019 Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, chloroquine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.