Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Chloroquine molecular formula Plaquenil 20 mg Plaquenil ga Hydroxychloroquine fibromyalgia Approach Considerations. Withdrawal of the medication and shifting to another form of treatment is the standard of care. No diet or medical therapy has been proven effective to prevent, treat, or reduce risk of retinal toxicity. Coordination with the rheumatologist or the dermatologist may be warranted for comprehensive care of the patient. Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Cessation of treatment may result in clearence but does not appear to affect the retinopathy. Cisplatin & Carmustine Used for treatment of malignant glioma & metastatic breast cancer Three types of retinal toxicity 1. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil retinopathy treatment Hydroxychloroquine and Chloroquine Retinopathy., Multimodal Imaging in Plaquenil Toxicity Hydroxychloroquine tablet uses in tamilPlaquenil drug manufacturerCan plaquenil help with fatigueHydroxychloroquine sulfate tablets ip The aminoquinolones chloroquine and hydroxychloroquine have been widely used in the treatment of SLE. These drugs can cause a reversible, visually insignificant keratopathy cornea verticillata and, more importantly, an irreversible sight-threatening maculopathy. Chloroquine Retinopathy - an overview ScienceDirect Topics. Drug induced maculopathy - EyeWiki. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity, which may be irreversible. Plaquenil or hydroxychloroquine is under the quinolone family. These medications are initially used in the prophylaxis and treatment of malaria. Plaquenil has replaced chloroquine because it produces less retinal side effects. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.