This fungus mainly grows in the central, southeastern, and mid-Atlantic states. Most cases of histoplasmosis don’t require treatment. Plaquenil insomnia Plaquenil and doxycycline Hydroxychloroquine 200 mg and alcohol Histoplasmosis occurs in patients with rheumatoid arthritis RA who receive corticosteroid therapy, disease modifying antirheumatic therapies such as methotrexate, and has been reported in post-marketing surveillance of patients receiving anti-tumor necrosis factor TNF therapy 4. A 61-year-old truck driver developed a fever, cough, and shortness of breath requiring oxygen support and antibiotics. He had rheumatoid arthritis controlled with methotrexate and hydroxychloroquine. His occupation required delivering produce to and from the Mississippi River Valley to Ontario, Canada. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is also used. The disease may progress and spread to other areas of the body. However, people with weaker immune systems may experience serious problems. Hydroxychloroquine with histoplasmosis Ocular Findings in Patients With Histoplasmosis, Histoplasmosis-induced pancytopenia Blood American. Chloroquine retinal cellChloroquine itching remedyPlaquenil skin itchingEye update plaquenil RESEARCH ARTICLE Open Access Histoplasmosis infection in patients with rheumatoid arthritis, 1998-2009 Timothy C Olson, Tim Bongartz, Cynthia S Crowson, Glenn D Roberts, Robert Orenstein and Eric L Matteson* RESEARCH ARTICLE Open Access Histoplasmosis infection in.. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Histoplasmosis Symptoms, Causes and Risk Factors.. Abstract. Miliary histoplasmosis is a rare presentation that may mimic miliary tuberculosis. We report a case of miliary histoplasmosis in a 52-year-old male who was being treated with hydroxychloroquine, methotrexate, and sulfasalazine for his rheumatoid arthritis and presented to the emergency department with shortness of breath and fevers. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Higher doses of medications that weaken your immune system are more likely to increase your risk of getting a fungal infection. 5,11,13,14. Click on the sections below to see lists of corticosteroids and TNF inhibitors that can increase the chances of getting a fungal infection.