Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil and hyperpigmentation Malaria chloroquine proguanil Abstract. Objectives. Neutropenia is an uncommon albeit relevant finding in patients with systemic lupus erythematosus SLE. It has been ascribed to several aetiologies and represents a challenging dilemma in which clinical findings, laboratory data and medication history must be carefully evaluated. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Introduction Hydroxychloroquine is a Aminoquinoline derivative which is widely used for treatment of malaria, rheumatoid arthritis and lupus besides many other autoimmune diseases. Though neutropenia is listed as a potential side effect, there is no reported case in the literature. We present a very rare presentation of hydroxychloroquine toxicity. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil and neutropenia Plaquenil and low wbc - Things You Didn’t Know, Hydroxychloroquine - Wikipedia Tests to get before starting hydroxychloroquineHydroxychloroquine action Oct 18, 2013 Lymphadenopathy can also be due to infection or a lymphoproliferative disease in SLE such as angioimmunoblastic T cell lymphoma which is characterized by arthritis, Coombs' positive hemolytic anemia, skin rash, fever, and weight loss 9. Splenomegaly occurs in 10%-46% of patients, particularly during active disease. Hematological Disorders in Patients with Systemic Lupus.. Hydroxychloroquine induced profound neutropenia with s.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Jan 01, 2020 Plaquenil is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. Plaquenil is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. Contraindications From the US Army Hospital, Camp Zama, Japan. Chernof is now at the City of Hope Medical Center, Duarte, Calif. A case of hydroxychloroquine-induced agranulocytosis in a patient with discoid lupus erythematosus is reported. The patient had previously received chloroquine therapy for several months.