I developed congestive heart failure and was taken off all RA meds except prednisone for a year. For years, I have been complaining to any of my doctors, who would listen, about the dizziness. I went back to my rheumatologist and he prescribed plaquenil again. In the beginning ( The first year or two) It really helped, with my symptoms, with lupus. This past two years, the dizziness has now, turned in to vertigo. Mg for an average person on plaquenil Chloroquine brand name Hydroxychloroquine alcohol Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Depending on what you're being treated for, it can take up to 6 months for the full benefits of Plaquenil hydroxychloroquine. Many people have nausea, stomach cramps, and diarrhea when they first start taking Plaquenil hydroxychloroquine. Now, that I have read this site, explanation of plaquenil, I think the mystery is solved. After taking it for 6 weeks, I had shortness of breath so I stopped taking it. Again, I have been trying to find out , what have been causing the vertigo. Plaquenil 6 months Plaquenil therapy and eye exams. - Eye Care - MedHelp, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Does plaquenil cause weight gain or lossHydroxychloroquine multiple sclerosisOct plaquenilAralen mechanism of actionIs plaquenil safe during breastfeeding When treating lupus or arthritis, Plaquenil is usually given daily for several weeks or months. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 months of treatment. While using Plaquenil, you may need frequent blood tests and vision exams. Plaquenil Uses, Dosage & Side Effects -. Compare Plaquenil vs Chloroquine -. Hydroxychloroquine Plaquenil. Plaquenil takes quite a long time to get to its peak effectiveness depending on what you read, anywhere from 3 months to a year. Unless you are having significant side effects, try to give it at least 6 months before you decide it doesn't work for you. Renal clearance in rheumatoid arthritis patients taking PLAQUENIL for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. Range for renal clearance of unchanged drug was approximately 16 to 30% and did not correlate with creatinine clearance; therefore, a dosage adjustment is not required for patients with renal impairment. I took plaquenil for 6 months and other medications for 2 years for RA. I developed congestive heart failure and was taken off all RA meds except prednisone for a year. I went back to my.