Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Question related to chloroquine What does plaquenil used for Taking Hydroxychloroquine develop toxicity2 It’s rare for side effects to occur with Plaquenil if the medication is dosed properly Side effects Blurred vision, bull’s eye maculopathy, scotoma, vortex keratopathy, headache, accommodative dysfunction, whitening of eyelashes, phototoxicity3 When using both these tools, keep in mind the following from Melles and Marmor’s recent study 1. “Retinal toxicity from hydroxychloroquine use cannot be completely prevented, but effective screening should recognize retinal toxicity before symptoms or significant risk of central vision loss appear ie. Rare side effects Vision changes/loss of vision There is a chance that retinal damage will occur while taking. Seeing light flashes/streaks/halos/blacked out areas of vision. Muscle weakness. Severe abdominal pain. Severe nausea/vomiting. Seizures. Shortness of breath. Any signs of. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil eye symptoms Conditions Plaquenil-related Eye Problems Eugene Eye Care, Plaquenil Risk Calculators Plaquenil synthesistChloroquine injection dose in malaria SYMPTOMS. Decreased vision; Photopsias; Glare; Metamorphopsia; Paracentral scotomas; Decreased night vision; Decreased color vision; TREATMENT. No treatment to reverse chloroquine or hydroxychloroquine toxicity. Recommend cessation of the medication, but visual function rarely recovers, especially in the later stages of the disease. Hydroxychloroquine Plaquenil Toxicity and.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil Side Effects Common, Severe, Long Term -. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. Overdose symptoms may include drowsiness, vision changes, slow heart rate, chest pain, severe dizziness, seizure convulsions, or shallow breathing. What should I avoid while taking Plaquenil? Avoid taking an antacid or Kaopectate kaolin-pectin within 4 hours before or after you take hydroxychloroquine. Plaquenil eye problems. Posted by Wesbig @wesbig, Jul 25, 2016. I was wondering if anyone experienced blurry vision on Plaquenil. I have been on Plaquenil for about a month. Every now and then I notice some of the words on the television are blurry, then there are other times my eyes are fine. Should this be a big concern?