These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil acute pancreatitis Plaquenil side effects hair loss Plaquenil and dementia Chloroquine hallucinations Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. BACKGROUND Hydroxychloroquine is used for the treatment of rheumatoid arthritis RA and systemic lupus erythematosus SLE. Long term studies have shown a high rate of termination of hydroxychloroquine treatment in patients with RA. Plaquinil long term.i am nervous of the side effects. could you please advise me on this it worth the risk of the side effects or should i just let my hair fall. View answer Answered by Dr. Ashakiran S General & Family Physician If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Side effects of long term plaquenil use Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Continuation of long term treatment with. Ocular effects of hydroxychloroquineCan plaquenil cause edemaHydroxychloroquine increase metroxtrateHydroxychloroquine vs hydroxychlorPlaquenil toxicity testing Feb 19, 2020 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil Hydroxychloroquine Side effects, Images, Uses.. Plaquenil long-term side effects - Doctor answers on.. Plaquenil Uses, Dosage & Side Effects -. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Incidence Not Known. Blistering, peeling, loosening of the skin. blurred vision or other vision changes. chest discomfort, pain, or tightness. cough or hoarseness. dark urine. decreased urination. defective color vision. In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The review is based on 48,938 people who have side effects while taking the drug from Food and Drug Administration FDA.