Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Pharmacological treatment with chloroquine inhibits autophagy in vivo Is plaquenil quinine Chloroquine phosphate saltwater Age, liver disease, and genetic factors e.g. polymorphisms in the cytochrome P450 gene which may impact blood concentrations are thought to be lesser risk factors associated with toxicity risk. Kidney and liver disease predispose to hydroxychloroquine toxicity due to impaired clearance of the drug. Plaquenil was originally approved by the Food and Drug Administration FDA in 1955. Plaquenil Warnings. Before taking Plaquenil, tell your doctor if you have or have ever had Liver disease. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. diabetes, kidney disease, liver. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and liver damage Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Hydroxychloroquine 20 mgPlaquenil bowel problems Find information about common, infrequent and rare side effects of Plaquenil Oral. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Plaquenil - Uses, Side Effects, Interactions -. What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito.