Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Prednisone and plaquenil lupus Plaquenil lyme disease Indications of chloroquine Chloroquine and primaquine dose Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Common side effects include headache; dizziness; loss of appetite; nausea; diarrhea; stomach pain; vomiting; nervousness; rash; Tell your doctor if you have any side effect that bothers you or does not go away. These are not all the possible side effects Plaquenil. For more information, ask your doctor or pharmacist. Side-effects and risks. Side-effects aren't common. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight. feeling sick nausea or indigestion. diarrhoea. headaches. bleaching of the hair or mild hair loss. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects long term Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol. Plaquenil and alcohol consumption In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The review is based on 57,733 people who have side effects while taking the drug from Food and Drug Administration FDA. Common Plaquenil side effects a study from FDA data.. Hydroxychloroquine Side-effects, uses, time to work. How long taking Plaquenil before side effects DailyStrength. More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Retinal Damage. Neurological Disorders. Blood Disorders. Hearing Disorders. Other Side Effects. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss.