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    Drug name: Glucophage XR, Cetapin XR Generic name: Metformin, Exermet Use: Type 2 diabetes Glucophage XR is an oral diabetes medication which contains the active ingredient metformin. Metformin is used to help control blood sugar levels in people with type 2 (non-insulin dependent) diabetes. It works firstly by reducing the amount of sugar produced by the liver. It also increases the sensitivity of muscle cells to insulin, which helps cells to remove sugar from the blood. It also has the action of delaying absorption of sugar from the intestines after a meal. Metformin thus reduces blood sugar levels both between and straight after eating. The possible Glucophage XR side effects include: • Headache, muscle pain; • Mild nausea, vomiting, diarrhea, gas, stomach pain; • Weakness, feeling faint. More serious side effects may include: • Feeling short of breath; • Fever, chills, body aches and other flu symptoms; • Symptoms of lactic acidosis; • Swelling or rapid weight gain. Metformin is one of the oldest drugs for the treatment of pancreatic diabetes type 2. The experience of this drug use was started in the beginning of 50th XX century, in the clinical practice. Metformin has been the most effective and stable drug to reduce the glucose level in the blood for more than 60 years. Metformin belongs to the list of the most important medical products of the World Health Organization. There are almost no drugs on the pharmaceutical market which acts quickly, effectively, and does not cause a lot of the side effects as Metformin. The pharmacological action of the drug consists in that reaching the body Metformin reduces the concentration of glucose in the blood by means of the reduction of the production of glucose in the liver. As the studies show the patients with pancreatic diabetes have the production of glucose in liver by 3 times higher than needed.

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