Vardenafil belongs to the class of medications called phosphodiesterase type 5 inhibitors. It is used to treat erectile dysfunction (male impotence). It helps to achieve penile erection sufficient for sexual activity to occur. It does this by allowing a greater blood flow into the penis when a man taking the medication is sexually aroused. It works only with sexual stimulation and does not increase sexual desire. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. zithromax warning Viagra (sildenafil), Cialis (tadalafil), or Levitra (vardenafil) are not safe to take if you have low blood pressure. In addition, taking drugs for erectile dysfunction (ED) along with alpha blockers like doxazosin mesylate (Cardura), prazosin hydrochloride (Minipress), and terazosin (Hytrin) to lower high blood pressure -- or with nitroglycerin and other nitrate-based drugs (for example, Isordil, Monoket, and Nitrostat) -- can cause a sudden, unsafe decrease in blood pressure. If you have low blood pressure, or are taking an alpha blocker or a nitrate-based drug, talk to your doctor about ED treatment that is right for you. Drugs that treat erectile dysfunction can lower blood pressure temporarily, and that can cause medical problems if you already have uncontrolled low blood pressure. We all know that high blood pressure (anything over 120/80) is unhealthy. But certain conditions, including certain kinds of heart disease, can cause blood pressure to be too low. Using an ED drug that further lowers your blood pressure is dangerous under these circumstances. 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Here's the good news: According to the American Heart Association, most people with heart trouble can enjoy sex safely -- and that includes those with high blood pressure. Sex -- like any other form of exercise -- does get the heart pumping. And, in rare cases, the extra exertion could trigger a heart attack. According to a report by the American Journal of Cardiology, fewer than 1 percent of all heart attacks occur during sexual activity. As reported in the journal, sex really can be dangerous for people with severe hypertension that isn't under control. If you have high blood pressure but aren't receiving treatment -- or if your blood pressure is soaring despite treatment -- your doctor may ask you to abstain from sex or other strenuous activity until your pressure is under control. If there's any doubt about your safety, your doctor will order a stress test to measure the effects of exercise on your heart. Whether you're a man or a woman, high blood pressure can definitely put a damper on your sex life. Among men, high blood pressure can cause erection problems by slowing the supply of blood to the penis. High blood pressure often has no signs or symptoms. Although sexual activity is unlikely to pose an immediate threat to your health — such as a heart attack — high blood pressure can affect your overall satisfaction with sex. Over time, high blood pressure damages the lining of blood vessels and causes arteries to harden and narrow (atherosclerosis), limiting blood flow. This means less blood is able to flow to the penis. For some men, the decreased blood flow makes it difficult to achieve and maintain erections — often referred to as erectile dysfunction. High blood pressure can also interfere with ejaculation and reduce sexual desire. Sometimes the medications used to treat high blood pressure have similar effects. Even a single episode of erectile dysfunction can cause anxiety. 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