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Xenical and phentermine Sildenafil oral tablet is a prescription medication used to treat erectile. an oral tablet, an oral suspension liquid, and an injection that's only given by a doctor. propecia for hair loss side effects Sildenafil is regarded as the most popular erectile dysfunction drug. Sildenafil was developed by a group of pharmaceutical chemists at Pfizer's facility in Kent, England who worked together to. Sildenafil injection - Learn more info about detail prescription, dosage, side effects, pregnancy effects, overdose, interactions. Sildenafil is an inhibitor of c GMP specific phosphodiesterase type-5 (PDE-5) in the smooth muscle of the pulmonary vasculature, where PDE-5 is responsible for degradation of c GMP. Sildenafil, therefore, increases c GMP within pulmonary vascular smooth muscle cells resulting in relaxation. In patients with PAH, this can lead to vasodilation of the pulmonary vascular bed and, to a lesser degree, vasodilatation in the systemic circulation. 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